L-Glutamic acid, N-[(phenylmethoxy)carbonyl]-, 1-(1,1-dimethylethyl) 5-methyl ester
Z-Glu(OMe)-OtBu
CAS: 57732-63-5
Molecular Formula: C18H25NO6
L-Glutamic acid, N-[(phenylmethoxy)carbonyl]-, 1-(1,1-dimethylethyl) 5-methyl ester - Names and Identifiers
L-Glutamic acid, N-[(phenylmethoxy)carbonyl]-, 1-(1,1-dimethylethyl) 5-methyl ester - Physico-chemical Properties
| Molecular Formula | C18H25NO6 |
| Molar Mass | 351.39 |
L-Glutamic acid, N-[(phenylmethoxy)carbonyl]-, 1-(1,1-dimethylethyl) 5-methyl ester - Upstream Downstream Industry
| Downstream Products | H-Glu(OMe)-OtBu |
L-Glutamic acid, N-[(phenylmethoxy)carbonyl]-, 1-(1,1-dimethylethyl) 5-methyl ester - Introduction
Z-Glu(OMe)-OtBu(Z-Glu(OMe)-OtBu) is an organic compound with the following properties:
Nature:
-Appearance: Colorless to light yellow solid
-Molecular formula: C16H23NO6
-Molecular weight: 325.36g/mol
-Melting point: about 65-68 ℃
-Solubility: Soluble in common organic solvents such as dichloromethane, methanol and acetonitrile
Use:
- Z-Glu(OMe)-OtBu is an organic synthetic intermediate for protecting amino acids, which is widely used in peptide synthesis and biomedical fields.
-It can be used as a starting material for the synthesis of more complex peptides, and other amino acids or functional groups can be added through it.
Preparation Method:
- Z-Glu(OMe)-OtBu can be synthesized by a variety of methods, one of the common methods is obtained by reacting phthalic anhydride and ethyl methoxyformate with L-glutamic acid and an appropriate activating reagent.
-During the synthesis process, tert-butyl p-toluenesulfonyl (Tosyl) is usually used as a protecting group to protect the amino group of glutamic acid, and benzyl is used as the side chain protecting group of amino acid.
Safety Information:
- Z-Glu(OMe)-OtBu is generally considered to be a relatively safe compound under normal operating conditions.
-But as an organic compound, it may still cause certain hazards to human health, such as irritation and sensitivity.
-During use, follow appropriate laboratory safety procedures, including wearing protective gloves and eyes, ensuring good ventilation, and avoiding direct contact with skin and inhalation of volatiles.
-In case of inadvertent exposure or any symptoms of discomfort, immediate medical attention and advice from a professional physician or toxicologist are recommended.
Nature:
-Appearance: Colorless to light yellow solid
-Molecular formula: C16H23NO6
-Molecular weight: 325.36g/mol
-Melting point: about 65-68 ℃
-Solubility: Soluble in common organic solvents such as dichloromethane, methanol and acetonitrile
Use:
- Z-Glu(OMe)-OtBu is an organic synthetic intermediate for protecting amino acids, which is widely used in peptide synthesis and biomedical fields.
-It can be used as a starting material for the synthesis of more complex peptides, and other amino acids or functional groups can be added through it.
Preparation Method:
- Z-Glu(OMe)-OtBu can be synthesized by a variety of methods, one of the common methods is obtained by reacting phthalic anhydride and ethyl methoxyformate with L-glutamic acid and an appropriate activating reagent.
-During the synthesis process, tert-butyl p-toluenesulfonyl (Tosyl) is usually used as a protecting group to protect the amino group of glutamic acid, and benzyl is used as the side chain protecting group of amino acid.
Safety Information:
- Z-Glu(OMe)-OtBu is generally considered to be a relatively safe compound under normal operating conditions.
-But as an organic compound, it may still cause certain hazards to human health, such as irritation and sensitivity.
-During use, follow appropriate laboratory safety procedures, including wearing protective gloves and eyes, ensuring good ventilation, and avoiding direct contact with skin and inhalation of volatiles.
-In case of inadvertent exposure or any symptoms of discomfort, immediate medical attention and advice from a professional physician or toxicologist are recommended.
Last Update：2024-04-09 15:18:02
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